• Arix announces investment in a new portfolio company focused on hematology, Disc Medicine

• Series B proceeds will enable Disc Medicine to advance its clinical programmes across multiple hematologic diseases
• Arix Managing Director Mark Chin will join Disc Medicine’s Board of Directors
• Arix joins financing round led by OrbiMed and syndicate of leading global biotech investors

LONDON, 2 SEPTEMBER 2021: Arix Bioscience plc (“Arix” or “the Company”), a global venture capital company focused on investing in and building breakthrough biotech companies, today announced that it has invested in Disc Medicine (“Disc”), a clinical-stage company focused on developing novel therapies to treat serious and debilitating hematologic disorders. As part of the financing, Arix has committed to invest $11 million (£8 million^[1]). Arix’s Managing Director Mark Chin will join Disc Medicine’s Board of Directors.

Based in Boston, MA, Disc Medicine has built a portfolio of first-in-class therapeutic candidates with the potential to address a spectrum of hematologic diseases, ranging from severe orphan conditions to widely prevalent conditions. The financing was led by OrbiMed and included new investors Janus Henderson Investors, 5AM Ventures, Rock Springs Capital and others as well as existing shareholders Atlas Venture, Novo Holdings, Access Biotechnology. Disc Medicine will use the proceeds from the financing to advance multiple programmes in Disc’s hematology pipeline into phase 2 development.

“Arix is delighted to participate in this financing for Disc Medicine, which is in line with our strategy of backing high potential biotech companies developing innovative treatments for serious unmet medical needs. With our strong balance sheet which has been bolstered by significant realisations, we are actively investing into the major biotech players of tomorrow. The field of hematology spans an enormous range of diseases but remains significantly underserved. Disc Medicine has built a platform around a world class management team and a pipeline of assets with compelling biology and strong validation to meet this need. I’m excited to join the board and be a part of the company’s future growth and success.”

Mark Chin, Managing Director at Arix and Board Director at Disc Medicine

“This financing will fuel the next stage of our company’s growth as we advance multiple programs into patient studies next year. I’m delighted to have Arix’s support in this round and want to extend a warm welcome to Mark as he joins the Disc Board. I’m looking forward to working together to make an impact on the lives of patients.”

John Quisel, Chief Executive Officer of Disc Medicine